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Screening and Characterization of Shark-Derived VNARs against SARS-CoV-2 Spike RBD Protein
Screening and Characterization of Shark-Derived VNARs against SARS-CoV-2 Spike RBD Protein Chen, Yu-Lei, Jin-Jin Lin, Huan Ma, Ning Zhong, Xin-Xin Xie, Yunru Yang, Peiyi Zheng, Ling-Jing Zhang, Tengchuan Jin, Min-Jie Cao ABSTRACT: The receptor-binding domain (RBD) of the SARS-CoV-2 spike protein is the major target for antibody therapeutics. Shark-derived variable domains of new antigen receptors
Sharks Provide Evidence for a Highly Complex TNFSF Repertoire in the Jawed Vertebrate Ancestor
Sharks Provide Evidence for a Highly Complex TNFSF Repertoire in the Jawed Vertebrate Ancestor Anthony K. Redmond, Rita Pettinello, Fiona K. Bakke, Helen Dooley ABSTRACT: Cytokines of the TNF superfamily (TNFSF) control many immunological processes and are implicated in the etiology of many immune disorders and diseases. Despite their obvious biological importance, the TNFSF repertoires
South Africa: Plett beaches closed after shark incident
News Release The National Sea Rescue Institute (NSRI) 25. September 2022 — — — — — — The NSRI and the Bitou Municipality appeal to the public to be cautious along the Plettenberg Bay and Southern Cape coastline. Beaches have been closed in Plettenberg Bay by Bitou Municipality. This sadly follows a fatal shark incident